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During the disease process, neutrophils usually play the dual role of “defense first and then damage.” In the early stage of disease, neutrophils play a protective role through phagocytosis and NETs to capture pathogens or remove aberrant proteins

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This mTORC1-dependent metabolic reprogramming produces numerous biochemical intermediates that are mechanistically connected to ferroptosis pathways ( 3.2.2 Regulatory T cells Treg cells are key inhibitory cells that maintain immune tolerance and escape of tumor cells